Survival Benefits and Risks of Lung Transplantation
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A lung transplant is a surgical procedure that involves replacing a diseased or failing lung with a healthy lung from a deceased donor. People who have tried medications or other treatments but whose conditions have not improved sufficiently are candidates for a lung transplant.
Lung disease or damage can make it difficult for your body to get the oxygen it requires to survive. A variety of diseases and conditions can harm your lungs and prevent them from working properly.
The following conditions may require lung transplantation:
Severe Cystic Fibrosis (CF). This is an inherited condition that causes problems with the glands that produce sweat and mucus. It is persistent, worsens over time, and is usually fatal. Bronchopulmonary dysplasia or chronic obstructive pulmonary disease (COPD). These are lung diseases that can affect normal breathing.
Pulmonary hypertension: This is an increase in blood pressure in the pulmonary arteries. Heart disease. Heart disease or heart defects that affect the lungs may require a heart-lung transplant. Pulmonary fibrosis: This is a lung scar.
Other Diseases Other conditions that can cause significant lung damage include sarcoidosis, histiocytosis, and lymphangioleiomyomatosis. Certain genetic disorders can also affect the lungs.
Types of lung transplant procedures include:
Lobe transplantation It is a surgical procedure in which part of a living or deceased donor's lung is removed and used to replace the recipient's diseased lung. In live donation, this procedure requires donating lung lobes from two different people, replacing her one lung on each side of the recipient. Adequately screened donors should be able to maintain a normal quality of life despite reduced lung volume. When transplanting dead leaves, one donor can provide both leaves.
Single lung. A single healthy lung transplant could save many patients. Donated lungs are usually from donors who have been declared brain dead
Double-lung Certain patients may need to have both lungs replaced. This is especially true for people with cystic fibrosis. This is due to bacterial colonization commonly found in the lungs of such patients. If only one lung is transplanted, bacteria from the original lung can infect the newly transplanted organ.
Heart-lung transplant. Some respiratory patients may also have serious heart disease requiring a heart transplant. These patients can be treated with surgery to replace both the lungs and heart with organs from one or more of her donors. A particularly complex example of this is referred to in the media as a "domino transplant". This type of transplantation was first performed in 1987 and typically involves transplanting a heart and lungs into recipient A and removing recipient A's healthy heart and transplanting it into recipient B.
Benefits of a lung transplant:
Lung transplant positively affects the overall quality of life. The main advantages of lung transplantation include: Increased life expectancy. About 55% of lung transplant patients have a survival rate of at least five years after a lung transplant. Other beneficiaries go on to live up to 10 and even 20 years. More energy. Many people who receive a lung transplant have more energy to participate in daily activities. Activities may include exercises and other physical activities. Increase fertility. It is possible to get pregnant after a lung transplant. Many women and AFABs report that their fertility has increased after a lung transplant. You should talk to your healthcare provider about the risks of trying to have a baby after a lung transplant.
A lung transplant has many risks, including:
Surgical risks: All surgeries have risks. Risks may include anesthesia complications, bleeding, blood clots, unfavorable scarring, infection and death.
Transplant rejection: Your immune system protects your body from foreign invaders that cause your body harm. External intruders include bacteria, viruses, parasites, and fungi. Transplant rejection occurs when the body's immune system attacks the transplanted lung. Interpret the lungs as foreign invaders. Transplant rejection occurs most frequently in the first 12 months after surgery (called acute rejection). Your doctor can in most cases reverse this form of rejection with additional immunosuppressants. There is a form of rejection called chronic rejection that can occur in some people more than three years after the transplant. When that happens, it becomes very difficult to treat and can lead to death or the need for another transplant. You will have to take immunosuppressants for the rest of your life. The drug reduces the risk of the immune system destroying new lungs. infection. Immunosuppressants slow or prevent the immune system from rejecting new lungs. However, a weakened immune system struggles to fight off infections.The risk of developing dangerous blood, fungal, skin, and respiratory infections is increased while taking immunosuppressive drugs.